From Chapter 1:
Perhaps the most likely scene of Raleigh's first experiments in the art of smoking was Durham House, which stood where the Adelphi Terrace and the streets between it and the Strand now stand. This was in the occupation of Sir Walter for twenty years (1583-1603), and he was probably resident there when Hariot returned from Virginia to make his report and instruct his employer in the management of a pipe. Walter Thornbury, in his "Haunted London," referring to the story of the servant throwing the ale over his smoking master, says: "There is a doubtful old legend about Raleigh's first pipe, the scene of which may be not unfairly laid at Durham House, where Raleigh lived." The ale story is mythical, but it is highly probable that Sir Walter's first pipes were smoked in Durham House. Dr. Brushfield quotes Hepworth Dixon, in "Her Majesty's Tower," as drawing "an imaginary and yet probable picture of him and his companions at a window of this very house, overlooking the 'silent highway':

From Chapter 6:
After King William III was settled on the throne the sum of £600,000 was paid to the Dutch from the English exchequer for money advanced in connexion with his Majesty's expedition, and this amount was paid off by tobacco duties. Granger long ago remarked that most of the eminent divines and bishops of the day contributed very practically to the payment of this revolutionary debt by their large consumption of tobacco. He mentions Isaac Barrow, Dr. Barlow of Lincoln, who was as regular in smoking tobacco as at his meals, and had a high opinion of its virtues, Dr. Aldrich, "and other celebrated persons who flourished about this time, and gave much into that practice." One of the best known of these celebrated persons was Gilbert Burnet, Bishop of Salisbury from 1689, and historian of his own times. He had the reputation of being an inveterate smoker, and was caricatured with a long clay stuck through the brim of the shovel hat, on the breadth of which King William once made remark. The bishop replied that the hat was of a shape suited to his dignity, whereupon the King caustically said, "I hope that the hat won't turn your head."